» Literaturhinweise  

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(10) Olson, J.E., Holtzman, D., Sankar, R., Lawson, C., Rosenberg, R."gOctanoic acid inhibits astrocyte volume control: implications for cerebral edema in Reye's syndrome". J. Neurochem. 52 (1989): 1197-1202.


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(12) Paul, H.S., Adibi, S.A. "Mechanism of increased conversion of branched chain keto acid dehydrogenase from inactive to active form by a medium chain fatty acid (octanoate) in skeletal muscle". J. Biol. Chem. 267 (1992): 11208-11214.


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(15) Kuge, Y., Yajima, K., Kawashima, H., Yamazaki, H., Hashimoto, N., Miyake, Y: "Brain uptake and metabolism of [1-11C]octanoate in rats: Pharmacokinetic basis for its application as a radiopharmaceutical for studying brain fatty acid metabolism". Ann. Nucl. Med. 9 (1995): 137-142.


(16) Rowley, H., Collins, R.C., [1-14C]"Octanoate: a fast functional marker of brain activity". Brain Res. 335 (1985): 326-329.


(17) Blei, A.T. "Fulminant hepatic failure". Liver Disease: Diagnosis and management. Hg.: B.R. Bacon und A.M. DiBesceglie. New York: Churchill Livingstone, 2000: 282-293.


(18) Blei, A.T., Olafsson, S., Therrien, G., Butterworth, R.F. "Ammonia-induced brain edema and intracranial hypertension in rats after portocaval anastomosis". Hepatology 19 (1994): 1437-1444.


(19) Norenberg, M.D., Bender, A.S. "Astrocyte swelling in liver failure: role of glutamine and benzodiazepines". Acta Neurochir. Suppl. 60 (1994): 24-27.


(20) James, J.H., Ziparo, V., Jeppsson, B., Fischer, J.E. "Hyperammonaemia, plasma amino acid imbalance, and blood-brain amino acid transport: a unified theory of portal systemic encephalopathy". Lancet 2 (1979): 772-775.


(21) Strom, R., Cardelli-Cangiano, P., Fiori, A., Ceci, F., Rossi Fanelli, F., Cangiano, C. "Ammonia, methylmercaptan, and blood-brain transport of amino acids". Advances in hepatic encephalopathy and urea cycle diseases. Basel: Karger, 1984: 273-289.


(22) Yaeko Ninomiya and Yukihiko Kayam: Inhibition of Choline Acetyltransferase Activity by Serum Albumin Modified with Octanoic Acid and Other Fatty Acids: Neurochemical Research 23; 10; (1998):1303 - 1311.


(23) Endo, Y. "In vivo deacetylation of N-acetyl amino acids by kidney acylases in mice and rats". Biochim. Biophys. Acta 628 (1980): 13-18.


(24) Fujita, Y., Anzai, M., Inui, M., Nishimoto, T., Inoue, G. "Utilization of N-acetyl-Ltryptophan given intravenously to unrestrained adult rats". J. Nutr. Sci. Vitaminol. 26 (1980): 381-388.


(25) Rose, W.C., Coon, M.J., Lambert, G.F. "The amino acid requirements of man. VIII. The metabolic availability of the optical isomers of acetyltryptophan". J. Biol. Chem. 212 (1955): 201-205.


(26) Wegmann, H., Curtius, H.C., Gitzelmann, R., Otten, A. "Nutritive value of Nacetyl-L-tryptophan in man". Helv. Paediat. Acta 34 (1979): 497-508.


(27) Ono, J., Hutson, D.G., Dombro, R.S., Levi, J.U., Livingstone, A., Zeppa, R. "Tryptophan and hepatic coma". Gastroenterology 74 (1978): 196-200.


(28) Knell, A.J., Davidson, A.R., Williams, R., Kantamanemi, B.D., Curzon, G. "Dopamine and serotonin metabolism in hepatic encephalopathy". Brit. Med. J. 1 (1974): 549-551.


(29) Carpenedo, R., Mannaioni, G., Moroni, F. "Oxindole, a sedative tryptophan metabolite, accumulates in blood and brain of rats with acute hepatic failure". J.Neurochem. 70 (1998): 1998-2003.


(30) Mannaioni, G., Carpenedo, R., Corradetti, R., Carla, V., Venturini, I., Baraldi, M.,Zeneroli, M.L., Moroni, F. "Tryptophan metabolism and hepatic encephalopathy. Studies on the sedative properties of oxindole". Adv. Exp. Med. Biol. 467 (1999): 155-167.


(31) Moroni, F., Carpenedo, R., Venturini, I., Baraldi, M. Zeneroli, M.L. "Oxindole in the pathogenesis of hepatic encephalopathy". Lancet 351 (1998): 1861.


(32) Kragh-Hansen, U. "Octanoate binding to the indole- and benzodiazepine-binding region of human serum albumin". Biochem. J. 273 (1991): 641-644.


(33) Tavares-Almeida, I., Gulyassy, P.F., Depner, T.A., Jarrard, E.A. "Aromatic amino acid metabolites as potential protein binding inhibitors in human uremic plasma". Biochem. Pharmacol. 34 (1985): 2431-2438.


(34) Takada, A., Grdisa, M., Diksic, M., Gjedde, A., Yamamoto, Y.L. "Rapid steadystate analysis of blood-brain transfer of L-Trp in rat, with special reference to the plasma protein binding". Neurochem. Int. 23 (1993): 351-359.


(35) Al Mardini, H., Harrison, E.J., Ince, P.G., Bartlett, K., Record, C.O. "Brain indoles in human hepatic encephalopathy". Hepatology 17 (1993): 1033-1040.


(36) Borg, J., Warter, J.M., Schlienger, J.L., Imler, M., Marescaux, C., Mack, G. "Neurotransmitter modifications in human cerebrospinal fluid and serum during hepatic encephalopathy". J. Neurol. Sci. 57 (1982): 343-356.


(37) Bergeron, M., Reader, T.A., Butterworth, R.F. "Early changes of serotonin turnover in brain following portocaval anastomosis: relation to altered sleep patterns and diurnal rhythms?" Progress in Hepatic Encephalopathy and Metabolic Nitrogen Exchange. Hg.: F. Bengtsson. Boca Raton: CRC Press, 1991: 219-232.


(38) Fernstrom, J.D., Wurtman, R.J. "Brain serotonin content: Physiological regulation by plasma neutral amino acids". Science 178 (1972): 414-416.


(39) Hamon, M., Bourgoin, S., Morot-Gaudry, Y., Hery, F., Glowinski, J. "Role of active transport of tryptophan in the control of 5-hydroxytryptamine biosynthesis". Adv. Biochem. Psychopharmacol. 11 (1974): 153-162.


(40) Hartmann, E., Spinweber, C.L. "Sleep induced by L-tryptophan". J. Nerv. Ment. Dis. 167 (1979): 497-499.


(41) Hoertnagl, H., Lochs, H., Kleinberger, G., Hackl, J.M., Hammerle, A.F., Binder, H., Wewalka, F. "Plasma catecholamines in hepatic coma and liver cirrhosis: Role of octopamine". Klin. Wschr. 59 (1981): 1159-1164.


(42) Noctor, T.A.G., Wainer, I. W., Hage, D.S. "Allosteric and competitive displacement of drugs from human serum albumin by octanoic acid, as revealed by highperformance liquid affinity chromatography, on a human serum albuminbased stationary phase". J. Chromatogr. 577 (1992): 305-315.


(43) Takikawa, H., Sugiyama, Y., Hanano, M., Kurita, M., Yoshida, H., Sugimoto, T. "A novel binding site for bile acids on human serum albumin". Biochim. Biophys. Acta 926 (1987): 145-153.


(44) Takada, A., Grdisa, M., Diksic, M., Gjedde, A., Yamamoto, Y.L. "Rapid steadystate analysis of blood-brain transfer of L-Trp in rat, with special reference to the plasma protein binding". Neurochem. Int. 23 (1993): 351-359



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